Anabasine-Synonym Neonicotine-obtained from the leaves of Duboisia myoporoides R. Br.

B. Anabasine

Synonym Neonicotine;
Biological Sources It is obtained from the leaves of Duboisia myoporoides R. Br. (Solanaceae) (Corkwood tree; Pituri); fruits and leaves of Nicotiana glauca R. Grah. (Solanaceae) (Tree Tobaccoclaimed to be the richest source of anabasine (1.2%); leaves of Nicotiana tabacum L. (Solanaceae) (Tobacco, Tabac, Virginia Tobacco); and also the leaves of Anabasis aphylla L. (Chenopodiaceae).
Chemical Structure 3-(2-Piperidixyl) pyridine; (C10H14N2).
Anabasine Synonym Neonicotine
Isolation Anabasine is extracted on a large scale in Russia; and the industrial extraction processes have been reported by Sadykov and Timbekov* (1956).
Characteristic Features
1. It is a liquid freezing at 9°C; and boiling at 270-272°C; bp14 145-147°C; bp2 105°C.
2. Its physical parameters are: d420 1.0455; nD20 1.5430; and [α]D20 -8310
3. It is soluble in most organic solvents and water.
Identification Tests
1. Being a secondary amine it can form a nitroso derivative.
2. Anabasine Hydrochloride: Its specific optical rotation is [α]D  +16.50 (C = 10 in water).
Uses It is invariably employed as an effective insecticide.
Source:Pharmacognosy And Pharmacobiotechnology By Ashutosh Kar

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