Jervine-obtained in the rhizomes of Veratrum grandiflorum, Veratrum album, Veratrum viride

B.2.2 Jervine


Biological Sources It is obtained in the rhizomes of Veratrum grandiflorum (Maxim.) Loes F. Veratrum album L., and Veratrum viride Sol. (Liliaceae).
Chemical Structure

Jervine
(3b, 23b)-17, 23-Epoxy-3-hydroxyveratraman-11-one (C27H39NO3).
Characteristic Features
1. The needles obtained from methanol and water has mp 243.5-244°C (Saito).
2. Its specific rotation [α]D20 150 - ∞ (ethanol) (Saito); and [α]D20 -167.6o (chloroform) (Poethke).
3. It has uvmax : 250, 360 nm (€ 1500, 60).
Identification Tests
1. Diacetyljervine (C31H43NO5): The diacetyljervine has mp 173-175°C; [α]D – 112°; uvmax (ethanol): 250, 360 nm (€ 16400, 80).
2. Jervine Hydrochloride has mp 300-302°C.

comment 0 nhận xét:

Post a Comment

 
© Pharmacognosy | Plants | herbal | herb | traditional medicine | alternative | Botany | © Copyright 2012 ; Email: epharmacognosy@gmail.com