Abstract :
Seven flavonoid
glycosides, including one new (1) and five previously uncharacterized (3-7),
were obtained from the seeds of lychee ( Litchi chinensis Sonn. cv. Heiye) by
means of repetitive column chromatography and high-performance liquid
chromatography (HPLC) preparation. They were identified as litchioside D (1),
(-)-pinocembrin 7-O-neohesperidoside (2), (-)-pinocembrin 7-O-rutinoside (3),
taxifolin 4'-O-beta-d-glucopyranoside (4), kaempferol 7-O-neohesperidoside (5),
tamarixetin 3-O-rutinoside (6), and phlorizin (7) on the basis of spectroscopic
analysis and comparison of their data to the values reported in the
literatures. Among them, compounds 1, 4, and 5 showed in vitro antitumor
activity against A549, LAC, Hep-G2, and HeLa cell lines in the
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric
assay.
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