Diosmin-Barosmin

2.4.1.2 Diosmin
Synonym Barosmin.
Biological Source It occurs in the dried Buchu leaves i.e.; various species of Barosma crenulata, Barosma serratifolia and Barosma betulina belonging to family Rutaceae. It has also been isolated from Serophularia nodosa, Hyssopus officinalis, Mentha crispa, Mentha pulegium and from species of Conium, Dahlia etc.
Description It occurs as pale yellow needles.
Chemical Structure The chemical structure of diosmin (5, 7, 3’-trihydroxy-4¢-methoxyflavone- 7-rhamnoglucoside) is given below:

Disomin upon hydrolysis yields rhamnose, glucose and the aglycone diosmetin.
Chemical Test A solution of diosmin in concentrated sulphuric acid exhibits a slight fluorescence.

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